The RAF has aired more than 100 people who had left Afghanistan and were in a neighboring third country to Britain.
The Ministry of Defense said the two planes had landed safely in the UK with 102 people who would receive support to begin their lives in the UK.
Repatriation flights and individual relocations have been running since the end of August, but this was the first military relocation of eligible Afghans and British nationals since the end of the Kabul evacuation.
Among the airborne were vulnerable Afghans who fall under the UK Government’s relocation and assistance policy, a scheme for former local staff and UK nationals.
More planes are scheduled to arrive in the UK in the coming weeks.
Defense Secretary Ben Wallace said the flights “mark the beginning of what will be a sustained effort to relocate and support those who need our help”.
“In August, we worked tirelessly to lift more than 15,000 vulnerable Afghans and British nationals from Kabul to Britain. As I made clear at the time, our commitment to the Afghan people did not stop there.
“We are determined to do the right thing for those who have supported our armed forces for so many years and others who are in danger.”
The MoD said the UK was working with international partners to ensure that as many routes as possible were available to those eligible and that the flights mean the start of “the next chapter of this effort”.
The ministry said the Home Office would treat and support the newly arrived Afghans who would be given indefinite leave to stay in the UK with funding allocated to schooling and health care.
The Foreign Office has also helped nearly 100 British nationals leave Afghanistan on Qatari flights since Britain’s last Kabul evacuation in August.
The news comes when Human Rights Watch said Taliban officials had forced thousands of people from their homes and land, violating international law, according to which collective punishment is illegal.
Many of the targeted individuals were members of the Shia Hazara community, and others had links to the former Afghan government. HRW said property and land seized in this way were often redistributed to Taliban supporters.